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Kaplan Qbank USMLE



Author7 Posts
  #1

A physiology question to some of you to think about…
What the hell happens to inulin?
If it’s neither reabsorbed nor secreted where the hell it does end up at?
Where does it go to? Please anyone can answer me this question…
It’s got to do with GFR
Renal physiology of course…


  #2

inulin is use for check GFR in nephrology field. it will detect glomeruli's filtration. due to it can be filtered 99%by Glomeruli of normal kidney thus, if you get 70% collected in terms of kidney glomeruli damaged. (both blood inulin and urine inulin concentration need to be detected).

  #3

The kidney does 3 things.....

1) Filters via glomeruli
2) Secretes (through several mechanisms)
3) reabsorbs (again, several mechanisms)

Inulin is ONLY filtered, and therefore it is a perfect indication of glomerular flitration capability. Inulin IS still removed from the body in this fashion. If anyone has anything to add or correct, please feel free to jump in...

Aron

  #4

It gets excreted.
As GFR is 20% of the Total Renal Blood Flow, 20% of Innulin is excreted in the urine.

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  #5

why does the hydronium ion concentration of an aqueous solution decrease when the hydroxide ion concentration increase?

  #6

because of acid-base balance

  #7

GFR=UwV/Pw=Cl

Inulin is apolysaccharide also

1) its freely filtered
2)not synthesized or broken down by the tubules
3) the w is inulin

clearance of a substance is the volume of plasma from which that substance is completely cleared by the kidneys per unit time

*its eventually excreted. Hope this helps (its conveniant to use creatinine

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