mani
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A 15 year old male underwent bone marrow transplantation, with marrow donated from a sibling, with a 5 out of 6 antigen match. He later developed a fine, scaling skin rash as well as diarrhea. The laboratory finding most likely to accompany this microscopic appearance is:
A Hyperamylasemia
B yperbilirubinemia
C Hypocomplementemia
D Neutrophilia
E Elevated creatine kinase
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| amitjosh
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GVHD - Hyperbilirubinemia
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| Malaysian
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I think its hyperbilirubinaenia too but for a different reason.
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| mani
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answers is B and amitjosh is rite in reasoning
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| Malaysian
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can you explain the reason for hyperbilirubinaemia due to GVHrejection then,mani?is it specific for this type of rejection?
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| mani
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i guess it is due to hemolysis + immune damage to liver, any comments?
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| Malaysian
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what type of hypersensitivity reaction is GVH rejection...1,2,3,4??
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| MLF
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Type 4
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| Robert8
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which bilirubin (conjugated or unconjugated) is elevated in this condition?
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| MLF
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Unconjugated
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| Malaysian
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ok thanks.....if anyone else wants give more points to the case above do fill us in.
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