tasneembanu
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is it serum ferritin?
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| noni
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In hemochromatosis ..there is increased serum iron,transferrin saturation and serum ferritin.....but normal tranferrin sat. and ferritin doesn't exclude the diagnosis.thus increased serum iron is more appropriate test .
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| dimps
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a transferrin saturation
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hi how r u
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| mdwannabe
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ferritin... serum Irom can be elevated in Fe overdose too...but ferritin elevation will occur in that case. So Ferritin is more specific for HC
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| asmi
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yep serum ferritin
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| mdwannabe
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and we in agreement yet again :-)
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"Life not lived for others, is not worth living" Uncle Einstein
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| noni
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what abt sideroblastic anamia and anamia of chronic disease???
serum ferritin is increased in them too.
:roll:
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| mdwannabe
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Serum Ferritin is not specific for any disease, it has to be taken in context of other CLINICAL findings and lab data. In this Q they say Hemosiderosis.
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"Life not lived for others, is not worth living" Uncle Einstein
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| asmi
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yep yet in agreement 
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| sar
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Transferrin saturation of >45% and serum ferritin of > 1000 ugm/L are reliable tests for hemochromatosis, I dont know which one is most appropriate?
I will go for serum ferritin.
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| chd_guy
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S ferritin is not increased in sideroblastic anemia. It is normal.
S ferritin and transferrin saturation are both increased in hemochromatois.
Harrison says both the test are not very specific if done alone but combined measurement of transferrin and S ferritin is relaible and if either of the test is abnormal genetic testing should follow (C282Y mutation)
But Harrison is more doubtuful of s transferrin levels as it gives more false positive and false negative results.
So I think the answer should be both and in this case S ferritin
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chd_guy
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| cache
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Ferritin is the answer, the information given above by the members is explanatory
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