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Yulia
Forum Elite Topics: 19 Posts: 240 |
What test helps you differentiate between Folate and B12 deficiencies in patient with megaloblastic anemia :?:
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Ouli Maty
| Forum Elite Topics: 33 Posts: 275
Schilling test?
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Yulia
| Forum Elite Topics: 19 Posts: 240
Excellent! The only thing is that in patients with severe and long standing folate deficiency cobalamine absorption can be decreased because of effect on intestinal mucosa. There's actually more than one test, that could help. But for the board purposes - you'll be choosing from the bunch of options. Serum levels of cobalamine or folate could be given. In case of B12 deficiency - methylmalonic aciduria is going to be present, which is a reliable sign (if patient doesn't have renal failure, but then again schilling test requires patient to have normal renal function). That's an interesting problem to look into 
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Ouli Maty
| Forum Elite Topics: 33 Posts: 275
I hope they will add some neurologic signs and thank you for the tips.
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rajeev
| Forum Junior Topics: 5 Posts: 62
MMA in the urine, most specific ..boom ! hit ur diagnosis and treat to prevent peripheral neuropathy
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Yulia
| Forum Elite Topics: 19 Posts: 240
That's what the question originally was about. You could also detect serum levels of MMA I suppose.
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NileSurgeon
| Forum Newbie Topics: 3 Posts: 28
nice one sure it's Schilling test
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