meghana jadhav
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An 8-month-old black female was brought to the emergency room with
shortness of breath, icterus and pallor under the tongue. The infant
measured below the 5th percentile for her age, despite weighing about the 80th percentile at birth. Examination of the peripheral smear indicates a hypochromic, microcytic anemia with some target cells and some teardrop-shaped erythrocytes. Hemoglobin electrophoresis reveals increased fetal hemoglobin (HbF) and double the normal amount of hemoglobin A2 (HbA2); there is very little hemoglobin A (HbA). There are no other hemoglobin bands.
7. Pathophysiology of this condition includes all of the following mechanisms
EXCEPT:
A. precipitation of insoluble a-globin aggregates
B. ineffective erythropoiesis
C. sequestration of inclusion-bearing RBCs
D. skeletal deformity due to lytic bone lesions
E. due to multiple blood transfusion
8. Which of the following conditions is most likely to develop in this infant by
adolescence?
A. asthma
B. Crohn’s disease
C. splenomegaly
D. chronic gastritis
E. iron deficiency
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megha
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| Ahab
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A
E
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| shawky2005
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This is a case of B thalassaemia .....
D (Skeletal deformity in thalassemia are not due to lytic lesions but due to massive expansion of the bone due to the ineffective erythroid production.
C (these patients are more liable to Hepatosplenomegaly .... in thalassemia there is no iron defeciency but there is iron overload ...
i hope the answers are right
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| mani
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i agree with shawky
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Sincerity and hard work are the keys to success!
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| shawky2005
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what are the correct answers meghana
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The way to America is too long, too hard and too expensive
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| Ahab
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not mine, i agree with the others. had a brain freeze at the time of posting. Been happening alot since i sat step 1  at least its after and not before
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| meghana jadhav
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u r right...shawky and mani...ans r correct...
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megha
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