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 non selective beta blocker-HT  




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Hi guys
I just donot fully understand why non selective beta blocker can contribute hypertenstion.
for beta-1 receptor part, non selective blocker can decrease HR, contractility, CO and decrease renin release to decrease BP.
how about fro beta-2 receptor part? beta-2 receptor blocker can vasoconstrict to increase BP? how this part can contribute the hypertension??

thanks!






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