Prep for USMLEPrep for USMLE
         Forum      |     Resources New Posts   |   Register   |   Login





 Drug Excipients  




Post Reply  
  • 0/5
  • 1
  • 2
  • 3
  • 4
  • 5


Author1 Posts
  #1

Hey,

does anyone have any hints on possible excipients that we could use in drug formulation for a drug with a weight of around 850 Da and being a class III or IV molecule aimed to target the liver?
So far we┬┤ve tried PEG400, 5% Tween 80 and at 5 hours after oral gavage our drug concentration in the liver peaked. We measured the concentration and calculated that around 0.002 % of it was going to the liver and we would love to have something around 5% if thats realistic wink

Thanks for any of your suggestions wink





Bookmark and Share





Login or Register to post messages








show Similar forum topics

drug-drug interactions
Which Drug ------- 3
Which drug ----- 2
show Related resources









Advertise | Support | Privacy | TOS | Premium | Contact