Prep for USMLEPrep for USMLE
         Forum      |     Resources New Posts   |   Register   |   Login

 Respiratory alkalosis-left shift?  

Post Reply  
  • 0/5
  • 1
  • 2
  • 3
  • 4
  • 5

Author2 Posts

Could somebody please explain why in respiratory alkalosis, there is a left shift in the oxygen binding curve??

Whereas, at high altitude,where there occurs resp alkalosis, there is right shift?


hey i think i can help u with this question.
shift to the right at high altitude is an adaptation. the body is trying to adapt to hyperventilation at high does it by increasing the conc of 2-3 bpg.this is in cases of chronic hypoxemia. 2-3 bpg binds to the beta chains of deoxy Hb and decreases the affinity of Hb for oxygen.thus promoting unloading of oxygen causing right shift.
in the other there is no high altitude so no 2 -3 bpg so shift to left!

Bookmark and Share

Login or Register to post messages

show Similar forum topics

Respiratory alkalosis-left shift?
Left-right shift?
Respiratory Alkalosis
show Related resources

Advertise | Support | Privacy | TOS | Premium | Contact