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WHY ARE SOME DISEASES CLASSIFIED AS TYPE 4 HYPERSENSITIVIES & AT THE SAME TIME HAVE AUTOANTIBODIES? (WHICH WOULD APPEAR AS CLASS 2)
Hashimoto thyroiditis, Type I diabetes mellitus & Guillain Barre syndrome are classified as type IV pathologies in which autoantibodies are present and used as clinical markers.
Nevertheless T lymphocytes are responsible for injuring the tissue by DTH or directly killing target cells.
Th1 lymphocytes > IFN γ > ⊕Macrophages > tissue damage
I got a hard time w/ this type of hypersensitivty
Edited by juanlink on Sep 24, 2015 - 12:38 PM
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Type II Hypersensitivity
Type IV hypersensitivity
What type of Hypersensitivity?
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