Bravo-man
Forum Junior
Topics: 4
Posts: 52
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In NMS Microbiology it says "heat-labile toxins(LT-I and LT-II) stimulate intestinal guanylate cyclase" while in Levinson and Cracking the boards the same LT "acts by stimulating adenylate cyclase". :|
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| dravedon
Forum Senior
Topics: 27
Posts: 74
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LT Toxins activates a G protein,which in turn stimulates the activity of a membrane-bound adenylate cyclase,resulting in the production of cAMP.
Intracellular cAMP results in active secretion of Na and Cl as well as inhibition of Na and Cl reabsorption.Fluid,bicarbonate and potassium are lost.
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| jeny
Forum Newbie
Topics: 2
Posts: 10
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ST toxin stimulate guanylate cyclase
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| meg
Forum Guru
Topics: 62
Posts: 806
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I agree with Jeny.
LT stimulates Adenylate cyclase
ST stimulates Guanyly cyclase
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| mjl1717
Forum Hero
Topics: 956
Posts: 5,452
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Kaplan concurs with what meg is saying.
I have a funny way of remembering it
LCAT (LAW COLLEGE ADMISSION TEST )FOR LT/ADENYLATE CYCLASE
STOP GONOCOCCEMIA FOR ST/GUANYLATE CYCLASE :shock:
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| meg
Forum Guru
Topics: 62
Posts: 806
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thanks mlj1717 
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