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Kaplan Qbank USMLE



Author8 Posts
  #1

what r the three mechanism by which cytotoxic T cell kill
the target cell?

___________________
megha

  #2

sorry this has to be in micro section.....

___________________
megha

  #3

Your excused this time. (my semi educated guess)

1)Collaborate with Bcells to produce antibody
2)Regulate immune response
3)dont know

___________________
Smell the coffee! "Is That an Osler move??"

  #4

its
1.perforins
2.granyzymes
3.fas-fas ligand

___________________
megha

  #5

what is granzyme?
i know fas is apoptosis receptor and perforin is involved in necrosis.

  #6

I believe granzymes are proteolytic enzymes that are released at the same time as perforin.

  #7

CTL cd8 pos functions:

1. release of perforins,granzyme( that is a protease which cuts and actives caspase 3) and granulysin.

2. Expression of fas-ligand

3. Release of IFN-gamma and Tnf-alpha and beta


  #8

granzimes start apoptosis







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