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Author5 Posts
  #1

how do ace inhibitors induce cough

  #2

probably has to do with mediation in the lungs by bradykinin,substance p or protaglandin. But for usmle your probably better off just knowing general mechanism of action and general side effects of all drugs.

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  #3

yep..it is the persistence of bradykinin in lungs. as well as systemically, causing angioedema in some cases.

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  #4

Addendum-First thing that hit my brain cells "bradykinin"-it was Goodman /Gillman who threw in Substance p and prostaglandin

___________________
Smell the coffee! "Is That an Osler move??"

  #5

Bradykinin B2 Receptor Gene Polymorphism Is Associated With Angiotensin-Converting Enzyme Inhibitor-Related Cough

got that from this site:

hyper.ahajournals.org/cgi/content/full/36/1/127









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