mjl1717
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Can anyone name( 2) alpha 1 agonist and (2) alpha 2 agonist?
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| carmenburana
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alpha-1
Methoxamine=mostly alpha-1, produces vasoconstriction at the arterioles, elev TPR and therefor increases BP. Used for paroxysmal supreventricular tachycardia and to correct halothane induced hypotension.
Phenylephrine+also mostly alpha-1, also a vaso constrictor, hypertensive agent, when given IV it produces reflex bradycardia, used in nasal decongestant sprays, eyedrops for mydriasis, also used for supraventricular tach
alpha-2
Clonidine=a "central-acting" hypotensive also good for symptomatic relief of withdrawal from opiates and benzos.
I can't find another alpha-2 agonist! Got one for me?
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| mjl1717
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methyldopa stimulates apha 2 preynaptic receptors and inhibits release of NE.
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