mash
Forum Fanatic
Topics: 147
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cold pain is carried by which nerve fibers?
A delta
C
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| PsychDr2B
Forum Elite
Topics: 35
Posts: 197
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Both
Cold
Detected by both Aδ and C fibers.
One type of receptor (designated TRPM8 or CMR1) is a channel that admits Ca2+ and Na+ in response to moderate cold or menthol (the ingredient that gives mint its "cool" touch and taste).
Lower temperatures (<17°C) elicit signals that the brain interprets at pain. These are mediated by transmembrane receptors designated ANKTM1. C fibers can contain both TRPV1 receptors (painfully hot) and ANKTM1 receptors (painfully cold).
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