arodny1
Forum Newbie
Topics: 10
Posts: 17
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Does anyone know a fast way to remember Hep B surface markers?? Like for active carrier, chronic carrier and pt treated for Hep B?? I keep getting confused..... please help. :? :?
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| mani
Forum Guru
Topics: 104
Posts: 1,403
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i dont have any pnemonic but i feel it easy if i consider the clinical significance of each marker
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| BumbleB
Forum Junior
Topics: 2
Posts: 83
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These are kinda heard to remmeber off the bat, but when you see them on the test they're pretty logical
HBsAg (and/or HBeAg) = prodrome
HBcAb and HBsAg (and or HBeAg) = acute disease
HBcAb (and or HbeAb only) = "window" or early convalescent stage
HBcAb and HBsAb = later convalescent stage
or here's a simpler guide:
incubation period = sAg
preodrom/disease = sAg+cAb
early convalesce = cAb
later convalescence = sAb+cAb
also
immmunized = sAb
The key is that cAb are made first, but sAb are the ones that give immunity to the virus, but these take about 6 months to develop - and some people never completely recover but remain in a carrier state. of course Igm cAb develop first, then IgG. Also, eAg is an indicatior of high infectivity for a carrier.
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| arodny1
Forum Newbie
Topics: 10
Posts: 17
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thanx alot bumbleb, that was really helpful!!
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