MLF
Forum Elite
Topics: 36
Posts: 386
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Could anybody explain why do we see polyuria in polio??
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| BumbleB
Forum Junior
Topics: 2
Posts: 83
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thats weird, i'd think you have anterior horn cell damage and LMN symptoms in the bladder - like flaccid paralysis and lack of micturition?
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| tonguo
Forum Senior
Topics: 29
Posts: 125
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i would guess its becoz paralysis of external urethral sphincter. its gotta be a skeletal muscle, which is innervated by the somatic system. totally guessing....
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| t-boat
Forum Newbie
Topics: 0
Posts: 6
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I think tonguo is right, since the external urethral sphincter is innervated by n.pudendus. in case of polio this innervation gets lost since polio has a effect on the anterior horn cells which leads to a paresis.
but polio also effects the functional equivalent neurons of the brainstem, which may be another reason of polyuria, since the pons contains the "miction center". this controls not only the miction-reflex but also the miction in general.
I hope I could help
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| BumbleB
Forum Junior
Topics: 2
Posts: 83
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As far as I learned polio only affects AH cells in the spinal cord, but I think it can probably spread up the spinal cord like HSV in rare cases and go upto the hypothalamus, into the supraoptic nucleus and maybe kill off the ADH cells.
I think the original question was asking why polio can cause POLYURIA (increased urine production) not INCONTINENCE, so I think its not asking about control over muscles, but rather about urine production.
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