santaclara
Forum Elite
Topics: 67
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Which of the following spirometry measurements has the greatest sensitivity for detecting early air flow obstruction?
A. FVC
B. FEV1
C. FFE
D. FEF25-75
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| mani
Forum Guru
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Posts: 1,403
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i think its FEV1
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| santaclara
Forum Elite
Topics: 67
Posts: 299
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i also thought "B" but answer is "d".
see this discription.
1:FEF25-75% is abbreviation of Forced expiratory flow during 25-75% of FVC (forced vital capacity).It is FLOW RATE not VOLUME as FEV1(forced expiratory volume in one second)
2:It is also called as MAXIMUM MID EXPIRATORY FLOW (MMEF)
3:It is affected maximally when there is obstruction in the small or medium sized airways.As you know in the respiratory tree ,max airway resistance is in MEDIUM SIZE AIRWAYS.
4:When there is obstructive element in ways ,naturally those airways which are ,already offering maximum resistance i.e medium size airways should be affected first, and their representative test FEF25-75% should show this change
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