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Kaplan Qbank USMLE



Author6 Posts
  #1

Which of the following is in the correct path of CO2 from the tissue to the atmosphere?
A. Reaction with H2O to make H2CO3, dissociation to H+ and HCO3-, H+ combines with imidazole side chain of hemoglobin, carried back to lungs as HHb+ and HCO3-, reverse reaction forms CO2.
B. O2 is metabolized to CO2, reaction with H2O to make H2CO3, H2CO3 combines with imidazole side chain of hemoglobin, H2CO3Hb+ is carried back to the lungs, reverse reaction forms CO2.
C. Reaction with H2O to make H2CO3, dissociation to H+ and HCO3-, HCO3- combines with imidazole side chain of hemoglobin, carried back to the lungs as HCO3-Hb+ and H+, reverse reaction forms CO2.
D. O2 is metabolized to CO2, reaction with H2O to make H2CO3, dissociation to H+ and HCO3-, carried back to lungs in this form, reverse reaction forms CO2.

  #2

I think its A, while the bicarb leaves the cell in the chloride shift, not too sure though, still have to revise respiratory

  #3

i m also thinking about "a" but what about "d" ahab?
is there any imidazole side chain of hemoglobin?
pls discuss it.
thanx.

  #4

its a. CO2 will combine with water within the rbc to from H2CO3 that dissociates to H+ and HCO3-, never trasported as H2CO3 neigher does H2CO3 ever combine with Hb itself.

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  #5

so mani this mean "A" is right? and there is an imidazole side chain of hemoglobin.
right ?
thanx for reply.

  #6

yes A is the answer

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