namf
Forum Elite
Topics: 80
Posts: 312
|
Hi USMLE folks,
I never really did understand the P-ANCA & C-ANCA--it was always just memorized as having something to do with PAN and for C-ANCA I can't even remember the association now...
Anybody want to point out the salient points 
Thanks for not diss-a-POINT-ing :shock: :roll: :lol:
|
| mani
Forum Guru
Topics: 104
Posts: 1,403
|
u need to remember it correctly
P for PAN and p-ANCA
c-ANCA is fro wegeners
___________________
Sincerity and hard work are the keys to success!
|
| namf
Forum Elite
Topics: 80
Posts: 312
|
Thanks Mani, and sorry for not being clear. I got the part about P for PAN and P-ANCA. But I still don't understand what the process is (what is P-ANCA? it sounds like Paul Anka or pee anger...it drives me nuts!!)
Thanks 
|
| mani
Forum Guru
Topics: 104
Posts: 1,403
|
perinuclear, antineutrophilic cytoplasmic antibody
___________________
Sincerity and hard work are the keys to success!
|
| adeelmd
Forum Elite
Topics: 40
Posts: 402
|
would that be type 3 hypersensitivity... anti-body neutrophil complexes getting stuck in kidneys, (for Wegner's) etc... or am i way off
___________________
where i lay my head is home.
|
| mdwannabe
Forum Guru
Topics: 37
Posts: 1,133
|
these are just the a/b found in the neutrophil. when a neut is studied under microscope after processing (flouresence prep) some a/b are found to collect around nucleus and others are in cytoplasm. So those aorund nucleus (p-ANCA) are found to be against Myelopeoxidase, those in periphery (c-ANCA) are found to be against Proteinase -3.
So both p and c ANCA are just descriptions of the pattern of flourence in the neutrophil being stidied.
The corelations with different conditions you already know.
Hope it helps.
___________________
"Life not lived for others, is not worth living" Uncle Einstein
"A life is not important, except in the impact it has on other lives" -Jackie Robinson
|
|
| |
| | | | | | |
