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Kaplan Qbank USMLE



Author7 Posts
  #1

a 55 old man with DM has burning dyesthesis on his lower leg,capsaicin containing cream alleviates his symptoms,what is responsible for his dyesthesias?

1.ADH
2.Dopamine
3.Ag II
4.inositol
5.neuropeptide Y
6.nitric oxide
7.NE
8.substance P

  #2

substance p

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  #3

I'd go for NO (6).
Substance P as far as i know it's a Pain neurotransmitter in the spinal cord
NO seems more like it to me because, generally in DM there is a microvascular disease - and vasodilation by NO might do the trick.
but I'm not sure... anybody else ..... ::very_confused::

  #4

well not, Sub P IS present in other parts of CNS in addition to Spinal cord and also is released from the peripheral axons when damaged as a part of "Axon Reflex" but about the Q i am not sure if it is responsible for dyesthesia....

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  #5

tasneembanu, do u have answer?

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  #6

i dont have the answer,i also thought it was substanse P

  #7

i, too, think the same

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