namf
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Hi gang!
Why in folate deficiency (megaloblastic anemia) do you have HIGH MCH, but LOW MCHC? I guess the low MCHC is the one I'd like an explanation for the most.
Thank you 
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| mash
Forum Fanatic
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MCH= Hb/RBC count
MCHC=Hb/Hct (Hct= RBC count*MCV)=MCH/MCV
in megaloblastic anemia MCV is high so, MCHC is low
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I hear and I forget. I see and I remember. I do and I understand.
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| Sakaki-
Forum Senior
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Isn't MCHC normal in folate deficiency (Harmening: Hematology)?
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| namf
Forum Elite
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Thanks Mash! Hi Sakaki--this q was straight from Qbank..which means it could be wrong of coure!
Anyone know?
Thanks again Mash-ster!
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| dariush
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as mash put it correctly : MCHC=MCH/MCV.
both MCH and MCV inc.(leading to HyperChromic+Macrocytic cells respectively) but MCHC doesnt change much (both denominator and numerator inc.!! )
mash i think it is the Fe-def in which MCHC also dec. am i wrong ?
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| mash
Forum Fanatic
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im sorry....u both r right, dariush and sakaki . MCHC decreases in Fe def anemia and is normal in megaloblastic anemia..
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I hear and I forget. I see and I remember. I do and I understand.
--Confucius
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| Sakaki-
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I'm positive that MCHC is used to assess whether cells are hypochromic, normochromic (or hyperchromic - though this term really isn't proper, from what I remember).
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