asmi
Forum Hero
Topics: 1043
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differentiate primary biliary cirrhosis and primary sclerosing cholangitis ?
what are the definitive diagnostic tests for both ?
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| dimps
Forum Guru
Topics: 63
Posts: 446
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primary billiary cirrhosis---autoimmune ds,destuction of intra hepatic bile ducts
seen mainly in woman
ass with other autoimmune disorders like RA ,sjogren,
AMAs can be found in 90-95% of patients with PBC, and they have a specificity of 98% for this disease
PSC--focal ds involving destruction of both intrahepatic &extrahepatic bile ducts
mainly in males
ass with IBD
ERCP and percutaneous transhepatic cholangiography (PTC) remain the preferred investigations
characterstic stricture bading seen on ERCP
plz correct me if i m wrong
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hi how r u
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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agree with you 
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| ICU-NUT
Forum Newbie
Topics: 0
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Since AMAs are so specific , when they are found in RA or sjogren does this mean that PBC definitely coexists?
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| dimps
Forum Guru
Topics: 63
Posts: 446
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M2 anti-mitochondrial antibodies are found in 90-95% of patients with primary biliary cirrhosis (PBC). A titre of greater than 50 IU/ml suggests PBC even in the absence of symptoms and in the presence of normal alkaline phosphatase
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