phuluong2k
Forum Fanatic
Topics: 714
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As my knowledge, The peptide formation by peptidyl transferase doesn't cost ATP or GTP, but in the Kaplan simulate test, One GTP is needed to form peptide bond
Any one can help me ?
Thank
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| dariush
Forum Elite
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Posts: 356
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actually the fact that it doesnt consume E doesnt mean that it comes for free !! if you remember from Kaplan, when AA-tRNA is Activating a high energy PPi bond is broken off (from an ATP yeilding AMP) which during peptide bond formation is used.
now the "2" GTPs metioned in Kaplan is used for 1)AA-tRNA binding to the ribosome and )TRANSLOCATION from A site to P site.
hope that helped.
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